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AJNR - American Journal of Neuroradiology

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Appearance of an Interhemispheric Cyst Associated with Agenesis of the Corpus Callosum

Annemarie Stroustrup Smith^a and Deborah Levine^b

^a Harvard Medical School and the Harvard-MIT Division of Health Science and Technology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215
^b Departments of Radiology and Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215

View larger version (116K): [in a new window]   FIG 1. Transabdominal sonogram obtained in a fetus with ACC and DWM at 27 weeks’ gestation. Coronal view shows elevation of the third ventricle, vertical orientation of the frontal horns (arrows), and absence of the corpus callosum.

View larger version (103K): [in a new window]   FIG 2. Single-shot half-Fourier turbo spin-echo MR images of the fetal brain at 27 weeks’ gestation. Coronal (A) and axial (B) images demonstrate agenesis of the corpus callosum and absence of any frontal cyst.

View larger version (78K): [in a new window]   FIG 3. Neonatal brain MR image taken when the patient was 1 day old. Axial T1-weighted image (similar plane to that of Figure 2B) shows the increased size of the frontal and occipital horns (compare with prenatal scan) in addition to the new finding of a frontal para-midline cyst (C).

View larger version (78K): [in a new window]   FIG 4. Neonatal cranial sonogram obtained when the patient was 5 days old. Coronal view in plane similar to that of Figures 2B and 3 demonstrates agenesis of the corpus callosum. In addition, a large frontal paramidline cyst is present (C).