Intraobserver Variability in the MR Determination of Tumor Volume in Squamous Cell Carcinoma of the Pharynx
Andrew R. Gordona,
Laurie A. Loevnera,b,
Amita Shukla-Davea,
Regina O. Redferna,
Adina I. Sonnersd,
Alex M. Kilgera,
Mark A. Elliotta,
Mitchell Machtayc,
Randal S. Weberb,
Jerry D. Glicksona and
David I. Rosenthalc
a Department of Radiology, University of Pennsylvania Medical Center, Philadelphia
b Department of Otorhinolaryngology: Head and Neck Surgery, University of Pennsylvania Medical Center, Philadelphia
c Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia
d the University of Pennsylvania School of Medicine, University of Pennsylvania Medical Center, Philadelphia
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FIG 1. MR imaging–based volumetric analysis of a carcinoma on the left side of the base of the tongue in a 54-year-old man.
A and B, Two sequential axial T2-weighted MR images (4000/100/2) were used to outline the primary tumor on each sequential axial image by using a mouse-controlled cursor. In this case, the neoplasm (outlined) is hypointense relative to the lymphoid tissue (L) of the lingual tonsil.
C, Serial axial T2-weighted MR images (4000/100/2) show all images where a primary tumor is present, and the outlines of the tumor on each section. A computer program calculated the volume by counting voxels included within the outlined regions.
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FIG 2. MR imaging–based volumetric analysis of a regional nodal metastasis in a patient with a primary cancer at the base of the tongue.
A and B, Two sequential axial T2-weighted images show how the nodal mass was outlined within a mouse-controlled cursor.
C, Serial axial T2-weighted MR images (4000/100/2) show all images on which nodal metastases are outlined and the outlines on each image.
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