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CT Findings in Kikuchi Disease: Analysis of 96 Cases

Soon-Young Kwona, Taik-Kun Kimb, Young-Sik Kimc, Ki Yeol Leeb, Nam Joon Leeb and Hae Young Seolb

a Department of Otolaryngology-Head and Neck Surgery, Korea University, College of Medicine, Seoul, South Korea
b Department of Diagnostic Radiology, Korea University, College of Medicine, Seoul, South Korea
c Department of Pathology, Korea University, College of Medicine, Seoul, South Korea



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FIG 1. Images obtained in a 28-year-old woman presenting with a 2-week history of fever, myalgia, and tender cervical lymphadenopathy.

A, CT scan shows multiple small and medium lymph nodes (arrows) on the left side of the neck (level III). Note the obliteration of perinodal fat at levels III and V and in the adjacent superficial space (arrowheads).

B, Photomicrograph of a surgical specimen from a lymph node shows patchy areas of lymphohistiocytic infiltration that does not distort the otherwise normal lymph node architecture (hematoxylin-eosin stain, original magnification x40).



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FIG 2. Images obtained in a 34-year-old woman.

A, CT scan shows small lymph nodes on the left at levels IIB and V. Note the ring-shaped nodal necrosis (arrow) mimicking that of tuberculosis or metastatic lymphadenopathy. Adjacent perinodal infiltration is also seen (arrowheads).

B, Photomicrograph of surgical specimen of lymph node shows a geographic pattern of eosinophilic necrosis and sheets of histiocytes (hematoxylin-eosin stain, original magnification x40). Inset, High-powered view of a necrotic focus shows abundant karyorrhectic debris (arrows) and crescent-shaped histiocytes (original magnification x400).