Advanced

AJNR - American Journal of Neuroradiology

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Schaefer, P. W. Articles by Gonzalez, R. G. Search for Related Content PubMed PubMed Citation Articles by Schaefer, P. W. Articles by Gonzalez, R. G.

Characterization and Evolution of Diffusion MR Imaging Abnormalities in Stroke Patients Undergoing Intra-Arterial Thrombolysis

Pamela W. Schaefer^a, Alvand Hassankhani^a, Christopher Putman^a, A. Gregory Sorensen^a, Lee Schwamm^b, Walter Koroshetz^b and R. Gilberto Gonzalez^a

^a Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston
^b Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston

View larger version (8K): [in a new window]   FIG 1. Images obtained in three patients in group B who had hyperintense regions at initial DWI that appeared normal at follow-up. Region 1 is DWI-hyperintense tissue that was abnormal at follow-up imaging. Region 2 is DWI-hyperintense tissue that was normal at follow-up imaging. A, ADC values in square millimeters per second. B, ADC ratios. C, DWI ratios.

View larger version (133K): [in a new window]   FIG 2. Reversal of DWI-hyperintense lesion after thrombolysis in a 68-year-old man with right-sided weakness and dysarthria. The patient had a left MCA occlusion that was successfully treated with IA tissue plasminogen activator at 6 hours. Initial DWI (row 1) and ADC (row 2) images demonstrate abnormality involving the left basal ganglia, insula, and subinsular region (short arrows) and in the left corona radiata (long arrow). At 3 days, follow-up (F/U) T2-weighted images demonstrate no abnormality in the left corona radiata. Lesions in the basal ganglia, insula, and subinsular region are unchanged. At discharge, the right-sided weakness had resolved.