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AJNR - American Journal of Neuroradiology

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Multiple Cerebral Aneurysms and Subarachnoid Hemorrhage in a Patient with Alagille Syndrome

Hans-Georg Schlosser^a, Thoralf Kerner^b, Christian Woiciechowsky^a and Goetz Benndorf^c

^a Department of Neurosurgery, Charité, Virchow-Clinic, Humboldt-University of Berlin, Berlin, Germany
^b Department of Anesthesiology and Critical Care Medicine, Charité, Virchow-Clinic, Humboldt-University of Berlin, Berlin, Germany
^c the Department of Radiology, Baylor College of Medicine, the Methodist Hospital, Houston, TX

View larger version (111K): [in a new window]   FIG 1. Cerebral (A-C) and abdominal (D-E) arteriograms demonstrate five intracranial aneurysms associated with multiple vascular abnormalities. Two saccular aneurysms of the right internal carotid artery are shown (A). The larger supraclinoid aneurysm (double arrow) caused the SAH and was treated by surgical clipping. The left internal carotid arteriogram (B) revealed a large infraclinoid aneurysm (double arrow) directed to the midline and an additional small aneurysm at the level of the origin of the ophthalmic artery (arrow). The left vertebral arteriogram demonstrated a broad-based aneurysm of the basilar tip (C). In addition, a coarctation of the aorta (D, double arrows), aneurysmal formations at the origin of the right renal artery and of the celiac trunk (E, arrows), as well as an aneurysm of the splenic artery (F, arrow) are shown.