AJDRAJNR - American Journal of Neuroradiology

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MR Imaging Findings of Uveal Leiomyoma: Three Cases

Kyung Joong Oha, Bae Ju Kwon, Moon Hee Hana,c,d, Pil Gyu Hwangb, Chong Jai Kimb, Dong Gyu Naa and Kee-Hyun Changa,c,d

a Department of Radiology, Seoul National University College of Medicine, Seoul, Korea
b Department of Pathology, Seoul National University College of Medicine, Seoul, Korea
c Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
d Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea



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FIG 1. A 24-year-old man with sudden decrease of left visual acuity.

A, Fundus photograph shows a dark, large, circumscribed, view-obstructing mass.

B, Transocular sonography reveals a well-marginated endophytic mass with low internal reflectivity (arrows). Subretinal effusion is also observed (arrowhead).

C, The mass located at the ciliochoroidal region is large, protuberant, and isointense to brain on a precontrast T1-weighted axial image (open arrow). Small amount of subretinal hemorrhage is noted (arrowhead).

D, T2-weighted fast spin-echo axial image also shows an intraocular mass isointense to brain.



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FIG 1. (continued) E, On gadolinium-enhanced T1-weighted axial image, a homogeneous, enhancing mass is seen at the ciliochoroidal region (open arrow), as is a small amount of nonenhancing subretinal hemorrhage around the posterior pole (arrowhead).

F, Low-magnification photograph of a cut specimen shows a well-circumscribed ciliochoroidal mass involving the whole stroma of the choroids (hematoxylin and eosin staining; magnification x2). C indicates ciliary body; E, subretinal effusion; L, lens; N, optic nerve; and T, tumor.

G and H, Hematoxylin and eosin staining (G) shows spindle cells arranged in intersecting fascicles, and tumor cells that have cigar-shaped nuclei with blunted end (arrowheads). The chromatin pattern is vesicular and mitotic figures are not seen. The tumor cells are positively stained for smooth muscle-specific actin (H).