Quantitative Proton MR Spectroscopic Findings of Cortical Reorganization in the Auditory Cortex of Musicians
Kubilay Aydina,
Koray Ciftcib,
Ege Terzibasioglua,
Mehmed Ozkanb,
Asli Demirtasc,
Serra Sencera and
Ozenc Minarecia
a Department of Radiology, Istanbul Medical School, Istanbul University, Istanbul, Etiler, Turkey
b Biomedical Engineering Institute, Bogazici University, Istanbul, Bebek, Turkey
c Department of Neurology, Sisili Etfal Research and Education Hospital, Istanbul, Sisli, Turkey
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FIG 1. T1-weighted MR images (530/20/3) depict examples of voxel placement.
A, Coronal MR image shows a voxel placed in the left planum temporale, which is located between the Heschl gyrus medially (arrow) and superior rim of the superior temporal gyrus.
B, Sagittal T1-weighted image shows location of the voxel.
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FIG 2. A, Image shows voxel placement for the phantom study.
B, Spectrum obtained from the phantom shows the acetate peak and lactate doublet.
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FIG 3. A–D, Proton spectra from the planum temporale in a musician, obtained with TE values of 30 ms (A), 48 ms (B), 135 ms (C), and 230 ms (D).
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FIG 4. A–D, Proton spectra from the planum temporale in a non-musician control subject, obtained with TE values of 30 ms (A), 48 ms (B), 135 ms (C), and 230 ms (D).
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FIG 5. A–C, Graphs show metabolite concentrations in musicians (M) and the non-musician control group (NM) for NAA concentration (A), Cr concentration (B), and Cho concentration (C). Error bars show 95% confidence intervals for the means of the metabolite concentrations.
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FIG 6. A, Graph demonstrates the relationship between NAA concentration in the musicians and total duration of musical training and activity. NAA concentration increases significantly as the duration of total musical training and activity increases (r = 0.733 [Pearson correlation coefficient], P = .016).
B, NAA concentration aganist age of commencement (r = –0.463, P = .178).
C, NAA concentration aganist time spent for musical activities per week (r = –0.327, P = .357).
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