Growth Rate of Corpus Callosum in Very Premature Infants
Nigel G. Andersona,
Isabelle Laurentb,
Nick Cookc,
Lianne Woodwardd and
Terrie E. Indere,f
Department of Radiology, Christchurch Hospital, Christchurch, New Zealand
b Department of Radiology, Grenoble Medical School, La Tronche, France
c Departments of Medical Physics and Radiology, Christchurch Hospital
d School of Education, University of Canterbury, Christchurch, New Zealand
e Murdoch Children’s Research Institute, Royal Women’s and Royal Children’s Hospitals, Melbourne, Australia
f Howard Florey Institute, Melbourne, Australia
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FIG 1. Sagittal midline cranial sonographic image shows the method for measuring height (double-headed arrow), and length (single-headed arrow) of the CC.
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FIG 2. Plot of postnatal growth rate of length of CC related to gestational age at birth in 64 very premature infants (32 boys) born at 23–33 weeks gestation. Dotted line represents the lower of 2 published growth rates of length of CC at prenatal sonography (13, 14). Growth rates are much lower (as much as 4-fold) in the very premature infant. Growth rate is from birth to term equivalency. The CC was measured by using cranial sonography.
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FIG 3. Plot of postnatal growth rate of length of CC related to length of CC at term equivalency in 64 very premature infants born at 23–33 weeks gestation. Growth rate is from birth to term equivalency. The CC was measured at cranial sonography. The slower the CC grows, the shorter it tends to be at term equivalency (linear regression R2 = 0.39). Symbols correspond to n-week gestation.
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