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Physiologic Variability of Single-Voxel Proton MR Spectroscopic Measurements at 3T

R. Mark Wellarda, Regula S. Briellmanna, Claire Jenningsa and Graeme D. Jacksona

a From the Brain Research Institute, Austin Health, Melbourne, Australia



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  		FIG 1. Frontal (left) and temporal (right) lobe spectra from a volunteer in the first (top) and second (bottom) sessions. Superimposed solid line corresponded to the LCModel fit, with the baseline shown below. Residual of the LCModel fit is inset above each spectrum. Peaks are labeled for NAA (NAA), creatine plus phosphocreatine (Cr), total trimethylamines (Cho), mI (mI), and glutamine and glutamate (Glx).



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  		FIG 2. Axial, coronal, and sagittal T1-weighted images show the location of voxels used for MRS acquisition.





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X