AJDRAJNR - American Journal of Neuroradiology

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Dilated Perivascular Spaces: Hallmarks of Mild Traumatic Brain Injury

Matilde Inglesea, Elan Bomsztyka, Oded Gonena, Lois J. Mannona, Robert I. Grossmana and Henry Rusineka

a From the Department of Radiology, New York University School of Medicine, NY



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  		FIG 1. Axial high-convexity T2-weighted images (TE/TR = 119/7900) from younger (A–C) and older (D–F) subjects. Note numerous enlarged VRS in B–F and their absence in A.

A, 28-year-old control subject.

B, 20-year-old patient imaged 7 days after trauma.

C, 27-year-old patient imaged 1.5 years after trauma.

D, 40-year-old control subject.

E, 42-year-old patient imaged 7 days after trauma.

F, 47-year-old patient imaged 1.7 years after trauma.



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  		FIG 2. Graph showing the correlation between the number of VRS and the age, expressed in years, in patients (squares) and control subjects (circles). VRS are associated with age (R = 0.69, P < .001) only in controls. Least-squares regression line indicates a significant linear relationship: no. of VRS = –4.9 + 0.250 (age in years). That is, the average increment is one VRS per 4-year increment of age.





Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X