Advanced

AJNR - American Journal of Neuroradiology

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Brubaker, L. M. Articles by Castillo, M. Search for Related Content PubMed PubMed Citation Articles by Brubaker, L. M. Articles by Castillo, M.

Hemodynamic and Permeability Changes in Posterior Reversible Encephalopathy Syndrome Measured by Dynamic Susceptibility Perfusion-Weighted MR Imaging

Lauren M. Brubaker^a, J. Keith Smith^a, Yueh Z. Lee^a, Weili Lin^a and Mauricio Castillo^a

^a From the Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, NC

View larger version (60K): [in a new window]   FIG 1. MR imaging of patient 1 within 24 hours of onset of symptoms. A, FLAIR MR image demonstrates bilateral posterior edema in the cortical and subcortical posterior brain. CBV (B) CBF (C), MTT (D), and K2 (E) maps illustrate a significant decrease in CBV, CBF, and MTT posteriorly, whereas K2 values are unchanged.

View larger version (30K): [in a new window]   FIG 2. Comparison of hemodynamic variables between normal subjects and patients with PRES. Graph shows ratio of values measured in the occipital lobe (posterior) to frontal lobe (anterior). Value of 1 is when posterior equals anterior. Notice significant increases in the ADC, as well as decreases in CBV and CBF, in posterior affected areas in patients with PRES. MTT shows considerable increased variability in PRES. K2 is unchanged.