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AJNR - American Journal of Neuroradiology

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Persistence of Congenital Mirror Movements after Hemiplegic Stroke

Maria A. Rocca^a,b, Domenico M. Mezzapesa^a, Maurom Comola^b, Letizia Leocani^b, Andrea Falini^c, Roberto Gatti^d, Silvia Mammi^b, Giancarlo Comi^b and Massimo Filippi^a

^a Neuroimaging Research Unit, Scientific Institute and University Ospedale San Raffaele, Milan, Italy
^b Departments of Neurology and Clinical Neurophysiology, Scientific Institute and University Ospedale San Raffaele, Milan, Italy
^c Department of Neuroradiology, Scientific Institute and University Ospedale San Raffaele, Milan, Italy
^d Rehabilitation Unit, Scientific Institute and University Ospedale San Raffaele, Milan, Italy

View larger version (127K): [in a new window]   FIG 1. Axial brain T2-weighted images of a patient with hereditary congenital MMs showing a large ischemic lesion in the left sylvian area, with microbleed components, and diffuse white matter hyperintensities in periventricular and subcortical regions.

View larger version (45K): [in a new window]   FIG 2. Color-encoded brain activations superimposed on a high-resolution T1-weighted image in the standard SPM space in a patient with congenital MMs during left hand movement (task 1). A, Clusters of activation are visible for the right and left primary SMC and right SMA. B, Cluster of deactivation is visible for the left SMA.

View larger version (45K): [in a new window]   FIG 3. Color-encoded brain activations superimposed on a high-resolution T1-weighted image in the standard SPM space in a patient with congenital MMs during left (A) (task 2) and right (B) (task 3) hand tactile stimulation. A, Cluster of activation is visible for the right primary SMC. B, Clusters of activation are visible for the right primary SMC and SMA and for the left precuneus.