A Novel Flexible, Retrievable Endovascular Stent System for Small-Vessel Anatomy: Preliminary In Vivo Data
Arnd Doerflera,b,
Wolfgang P. H. Beckera,
Isabel Wankea,
Sophia L. Goerickea,
K. M. Muellerc,
Nina Blechschmida,
Achim Flesserd,
Hermann Monstadtd and
Michael Forstinga
a Department of Neuroradiology, Institute of Diagnostic and Interventional Radiology, University of Essen Medical School, Essen, Germany
b Department of Neuroradiology, University of Erlangen Medical School, Erlangen
c Department of Pathology, University of Bochum Medical School, Bochum, Germany
d Dendron-MTI, Bochum, Germany
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FIG 1. Illustrative benchmark testing of the stent system.
A, Prototype stent manufactured with 4-mm diameter. The platinum/nitinol alloy stent is attached to a steel delivery wire and detached by electrolysis of an uninsulated junction zone.
B, Stent partially retrieved into the microcatheter.
C, Deployed stent in an aneurysm glass model around a 90° bend mimicking basically a wide-necked carotid-ophthalmic aneurysm treated with coils.
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FIG 2. Multimodal imaging before and after stent placement.
A, Intraarterial angiogram of the right common carotid artery before stent placement.
B, Plain radiograph showing the stent partially deployed within the vessel. Note the junction zone still within the microcatheter (arrow).
C and D, Intraarterial angiogram (plain and unsubtracted) immediately after stent deployment. Note the slightly irregular vessel surface at the stent site and the slight distal narrowing (arrows) due to vasospasm.
E and F, MR angiography, TOF (E) and contrast-enhanced (F) 3 days after stent implantation. The nitinol stent induces artifacts mainly at the proximal stent site due to the marker.
G and H, CT angiography, sagittal reformation (G) depicts the stent. 3D images (H) demonstrating the open vessel. Note the slightly irregular vessel surface at the stent site.
I, Intravenous angiogram 4 weeks after stent deployment. Note the second stent placed into the right subclavian artery (diameter 2.5 mm, length 20 mm). Both vessels are open without narrowing.
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