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Perfusion CT for Head and Neck Tumors: Pilot Study

Zoran Rumboldta, Riyadh Al-Okailia and John P. Deveikisa

a From the Department of Radiology, Medical University of South Carolina, Charleston



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  		FIG 1. Patient 8 with atypical vascular proliferation of the vocal cord.

A, Contrast-enhanced neck CT scan shows a mass in the left true vocal cord. ROIs 9 and 11–13 are in the lesion, and ROI 10 is in the contralateral vocal cord.

B, CTP functional map shows a relatively low blood flow of 26–32 mL/100 g/min in the lesion in the left vocal cord. Right vocal cord has blood flow of 26 mL/100 g/min. Scale from red to blue corresponds to decreasing flow.

C, CTP functional map shows that the lesion has a relatively long MTT of 6.9–11.6 seconds. Scale from red to blue corresponds to increasing MTT.



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  		FIG 2. Patient 3 with surgically treated acinic cell cancer of the parotid gland.

A, Rater 1. Contrast-enhanced neck CT scan shows a mass in the suboccipital subcutaneous fat (arrow) that was a suspected metastatic lymph node. Histology showed fat necrosis and chronic inflammation. ROIs are placed on the lesion (1) and on the masseter (3) and paraspinal (5) muscles.

B, Rater 2. CTP functional map shows relatively low blood flow of 24.9 mL/100 g/min in the lesion (arrow, ROI 1) and shows ROIs in the masseter (4) and paraspinal (8 and 9) muscles. Scale from red to blue corresponds to decreasing flow.

C, Rater 2. CTP functional map shows that the lesion (arrow, ROI 1) has a relatively long MTT of 10.5 seconds and shows ROIs in the masseter (4) and paraspinal (8 and 9) muscles. Scale from red to blue corresponds to increasing MTT.



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  		FIG 3. Patient 12 with primary gingival squamous cell cancer.

A, Contrast-enhanced neck CT scan shows a mass on both sides of the left mandibular body (arrows).

B, Lesion is more conspicuous on the CTP functional map, which reveals a high blood flow of 96–144 mL/100 g/min. Scale from red to blue corresponds to decreasing flow.

C, CTP functional map shows that the lesion has a short MTT of 2.1–5.4 seconds. Scale from red to blue corresponds to increasing MTT. The ROIs were placed within the lesion (8 and 9), paraspinal muscles (10), and left parotid gland (11).



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  		FIG 4. Patient 13 with recurrent laryngeal squamous cell cancer previously treated with radiation.

A, Contrast-enhanced neck CT scan shows thickening and diffuse enhancement of supralaryngeal structures. ROIs 1 and 2 are placed bilaterally in the abnormality. Both sampled sites were positive for recurrence on histology. ROI 4 is in the left sternocleidomastoid muscle.

B, CTP functional map reveals areas of increased perfusion with blood flows of 67 and 77 mL/100 g/min. Scale from red to blue corresponds to decreasing flow.

C, CTP functional map shows short MTTs of 2.5 and 3.4 seconds in the abnormality. Scale from red to blue corresponds to decreasing MTT.





Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X