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AJNR - American Journal of Neuroradiology

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Selective Intraarterial Nimodipine Treatment in an Experimental Subarachnoid Hemorrhage Model

M. Murat Firat^a, Veli Gelebek^a, Hakan S. Orer^b, Deniz Belen^c, Ahmet K. Firat^a and Ferhun Balkanci^a

^a Department of Radiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
^b Department of Pharmacology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
^c Department of Neurosurgery, Social Security Hospital, Ankara, Turkey

View larger version (54K): [in a new window]   FIG 1. Rabbit angiograms. A, Baseline measurements. B, During vasospasm. C, Following IA nimodipine treatment. Insets show enlarged portions of the corresponding angiograms. Measured diameters are given as transecting lines.

View larger version (23K): [in a new window]   FIG 2. Changes in vertebral artery diameters in different treatment groups. Values are obtained from five experiments. Asterisk indicates a value that is statistically significant from spasm values (P < .05).

View larger version (22K): [in a new window]   FIG 3. Changes in basilar artery diameters in different treatment groups. Values are obtained from five experiments. Asterisk indicates a value that is statistically significant from spasm values (P < .05).