MR Imaging-Based Volumetry in Patients with Early-Treated Phenylketonuria
Nadine H. Pfaendnera,
Gitta Reunerb,
Joachim Pietzb,
Gregor Josta,
Dietz Ratingb,
Vincent A. Magnottac,
Alexander Mohra,
Bodo Kressa,
Klaus Sartora and
Stefan Hähnela
a Division of Neuroradiology, Department of Neurology, University of Heidelberg Medical Center, Heidelberg, Germany
b Department of Pediatric Neurology, University of Heidelberg Medical Center, Heidelberg, Germany
c Department of Psychiatry, Iowa Mental Health Clinical Research Center, University of Iowa, Iowa City, IA

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FIG 1. Bar graph shows relative volume differences of several brain structures and relative difference of two-dimensional extension of the corpus callosum (call) in phenylketonuria versus the normal group. Pons and hippocampus (hippo) are the most severely affected structures. cbr = cerebrum.
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