The Effect of Prior Surgery on Blood Oxygen Level–Dependent Functional MR Imaging in the Preoperative Assessment of Brain Tumors
Michael J.J. Kima,
Andrei I. Holodnya,
Bob L. Houa,
Kyung K. Pecka,
Chaya S. Moskowitzb,
Dmitry L. Bogomolnya and
Philip H. Gutinc
a Department of Radiology, Functional MRI Laboratory, Memorial Sloan-Kettering Cancer Center, New York, NY
b Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY
c Department of Neurosurgery, Memorial Sloan-Kettering Cancer Center, New York, NY
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FIG 1. Average volume of activation measurements in prior-surgery (PS) and no-prior-surgery (NPS) groups. There is a marked decrease in the tumor side activation volumes of patients with prior surgery.
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FIG 2. In patient 40, there is robust activation in the right motor cortex but little detectable activity in the left motor cortex. In the T2-weighted image (A), the area containing the signal intensity void (arrow) corresponds to the physical location of a titanium plate installed during a prior operation. The susceptibility artifact is not visible in the T1-weighted image (B).
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FIG 3. In patient 33, the location of the susceptibility artifact is further away from the motor cortex than in patient 40 (Fig 2). Correspondingly, the signal intensity dropout is less severe.
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