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Effects of Aging on Regional Cerebral Blood Flow Assessed By Using Technetium Tc 99m Hexamethylpropyleneamine Oxime Single-Photon Emission Tomography with 3D Stereotactic Surface Projection Analysis

Kazuo Takahashia, Shuhei Yamaguchia, Shotai Kobayashia and Yasushi Yamamotob

a Departments of Neurology, Hematology, and Rheumatology, School of Medicine, Shimane University , Shimane, Japan
b Radiological Center, Shimane University Hospital , Shimane, Japan



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  		FIG 1. Statistical maps analyzed by 3D SSP. The color of the outer counter corresponds to a Z score of 7.

A, Relative decreases of rCBF (z score less double equals2) in subjects 60–69 years of age compared with rCBF in subjects 50–59 years of age. The most extensive reduction in rCBF was observed in the right anterior cingulate gyrus. There were also decreases in rCBF in the left anterior cingulate gyrus, bilateral posterior cingulate gyri, bilateral medial frontal gyri, bilateral subcallosal gyri, left superior temporal gyrus, and left cuneus.

B, Relative decreases of rCBF (z score less double equals2) in subjects 70–79 years of age compared with rCBF in subjects 60–69 years of age. The most extensive reduction in rCBF was observed in the bilateral anterior cingulate gyri. There were also decreases in rCBF in the left inferior frontal gyrus, left subcallosal gyrus, left supramarginal gyrus, and left superior temporal gyrus.

C, Relative decreases of rCBFs (z score less double equals2) in subjects 70–79 years of age compared with rCBF in subjects 50–59 years of age. The most extensive reduction in rCBF was observed in the bilateral anterior cingulate gyri. There were also decreases in rCBF in the left inferior frontal gyrus, left subcallosal gyrus, left supramarginal gyrus, and left superior temporal gyrus.





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X