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AJNR - American Journal of Neuroradiology

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Does a Relative Perfusion Measure Predict Cerebral Infarct Size?

Tobias Engelhorn^a, Arnd Doerfler^a, Michael Forsting^a, Gerd Heusch^b and Rainer Schulz^b

^a Department of Neuroradiology, University Hospital, Essen and Erlangen, Germany
^b Institute of Pathophysiology, University Hospital, Essen and Erlangen, Germany

View larger version (54K): [in a new window]   FIG 1. TTC-stained brain sections on the level of the optic chiasm. The white or grayish tissue is unstained and is equivalent to necrotic tissue. The upper section demonstrates a complete infarction of the MCA-supplied territory. Borders of the parietal, temporal, and piriform cortex are outlined as well as the basal ganglia. The middle section demonstrates partial necrosis of the temporal cortex, whereas the lower sections demonstrate complete necrosis.

View larger version (22K): [in a new window]   FIG 2. Relationships between absolute CBF and relative CBFC at 30 minutes post-MCAO and infarct size in groups A (A) and B (B) (expressed as percentage of total brain size). Hkt indicates hematocrit.