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AJNR - American Journal of Neuroradiology

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Influence of Partial Volume on Venous Output and Arterial Input Function

I. van der Schaaf^a, E.-J. Vonken^a, A. Waaijer^a, B. Velthuis^a, M. Quist^b and T. van Osch^a,c

^a Department of Radiology, University Medical Center Utrechtv, Best, the Netherlands
^b Philips Medical Systems, Best, the Netherlands
^c Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands

View larger version (98K): [in a new window]   Fig 1. A circular region of interest with a standard size of 2.5 cm in diameter was drawn in the peripheral anterior flow territory at the level of the basal ganglia on a standard location containing both white and gray matter. The location of the measurement of the AIF (artery) and the VOF (vein) are also indicated.

View larger version (13K): [in a new window]   Fig 2. Mean AUC for the VOF (A), AIF (B) and mean widths of the AIF (C) for 12-mm (), 6-mm (), and 3-mm (•) section thickness in 10 patients. In all patients, a smaller section thickness results in an equal or larger AUC of the VOF (A) and AIF (B). The width of the AIF decreases slightly (C) with a smaller section thickness in most patients.

View larger version (11K): [in a new window]   Fig 3. Raw attenuation curves of the optimal VOF for 12-mm (), 6-mm (), and 3-mm (•) section thickness (same patient as in Fig 1).