Intracranial Compartment Volumes in Normal Pressure Hydrocephalus: Volumetric Assessment versus Outcome
W.M. Palm,
R. Walchenbach,
B. Bruinsma,
F. Admiraal-Behloul,
H.A.M. Middelkoop,
L.J. Launer,
J. van der Grond and
M.A. van Buchem
Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands
Department of Neurosurgery, Leiden University Medical Center, Leiden, the Netherlands
Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands
Department of Neuroepidemiology Section, National Institute on Aging, Bethesda, Md
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Fig 1. Intracranial semiautomated segmentation was based on axial T2 (A) and proton attenuation–weighted images. The outer contour of the subarachnoid space was manually delineated on each section (B). This was followed by an automated segmentation procedure that assigned brain tissue and CSF within this region. We determined TICV, ventricular volume (C), brain volume, and pericerebral CSF volume (D).
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