Resectability Issues with Head and Neck Cancer
D.M. Yousema,
K. Gada and
R.P. Tufanob
a Russell H. Morgan Department of Radiology and Radiological Sciences, Division of Neuroradiology, Johns Hopkins Medical Institution, Baltimore, MD
b Department of Otolaryngology, Johns Hopkins Medical Institution, Baltimore, MD
View larger version (70K):
[in a new window]
|
Fig 1. Carotid encasement; adenoid cystic carcinoma. A, Note the circumferential involvement of the left cavernous artery by a soft-tissue mass with narrowing of the carotid artery in this patient who had adenoid cystic carcinoma from the sinonasal cavity. B, This patient also demonstrates erosion of the clivus with bony infiltration of the skull base.
| |
View larger version (105K):
[in a new window]
|
Fig 2. Carotid fixation. This patient who had recurrent thyroid cancer in the left side of the neck demonstrates effacement of the fat planes around the left CCA laterally (black arrow). Nonetheless, the tumor does not extend greater than 270° around the circumference of the carotid artery, and the tumor was able to be stripped off the carotid artery at surgery. Note also the tumor abutting the anterior scalene muscle on the left side (white arrow). In many instances, the head and neck surgeons believe that this is a contraindication for further surgery due to the potential for brachial plexus involvement.
| |
View larger version (166K):
[in a new window]
|
Fig 3. Prevertebral muscular infiltration. This T1-weighted scan demonstrates a left tonsillar carcinoma, which causes effacement of the fat of the retropharyngeal space on the left. Compare the left side with the right side. The irregular margin of the muscle belies the infiltration of the longus colli in this patient with fixation of tumor.
| |
View larger version (114K):
[in a new window]
|
Fig 4. Gross infiltration of the laryngeal cartilage. Erosion of the right side of the cricoid cartilage (long arrow) is well demonstrated in this patient with laryngeal carcinoma with subglottic extension. Additionally, the anterior margin of the right thyroid cartilage (short arrow) appears to be invaded.
| |
View larger version (81K):
[in a new window]
|
Fig 5. Laryngeal cartilage sclerosis. Axial postcontrast CT scan at the level of the true vocal cord shows sclerosis of the right arytenoid cartilage (arrow), associated with thickening of the true vocal cord. This finding is suggestive of cartilaginous invasion or perichondrial reaction.
| |
View larger version (63K):
[in a new window]
|
Fig 6. Arytenoid sclerosis in laryngeal carcinoma. Axial CT scan with bone windows shows a sclerotic right arytenoid cartilage (arrow) in a patient with true vocal cord cancer. Despite the sclerosis, there was no evidence of cartilaginous invasion on histology.
| |
View larger version (80K):
[in a new window]
|
Fig 7. Dural and intracranial extension of mass. A, Axial T2-weighted scan demonstrates soft-tissue mass infiltrating the anterior cranial fossa with associated edema of the right frontal lobe. B, Parasagittal T1-weighted scan shows the gross infiltration across the cribriform plate to involve the anterior cranial fossa with massive involvement in an extra-axial location. C, Postcontrast fat-suppressed T1-weighted scan shows intracranial extension as well as dural infiltration and pial extension of tumor adjacent to the midline. D, A different patient with adenocarcinoma of the paranasal sinuses shows considerable thickening of the dural greater than 5 mm, indicative of dural infiltration, confirmed at surgery.
| |
View larger version (131K):
[in a new window]
|
Fig 8. Post–gadolinium-enhanced scan through the floor of the mouth demonstrates a contrast-enhancing mass (arrow) infiltrating the right side of the mandible and extending into the subcutaneous tissue. There is an associated mass at the right lateral base of the tongue. Note infiltration of the mandible extends across the midline.
| |
View larger version (157K):
[in a new window]
|
Fig 9. Infiltration of the mandible with retropharyngeal spread of tumor. Axial T1-weighted scan demonstrates a large mass emanating from the right palatine tonsil extending along the floor of the mouth posteriorly to infiltrate the right side of the mandible. Note that the signal intensity of the right side of the bone marrow is dark, replacing the bone marrow fat. There is effacement of the retropharyngeal fat on the right side, with tumor abutting the longus colli/capitis muscle complex.
| |
View larger version (140K):
[in a new window]
|
Fig 10. Sarcoma growing into the left maxilla. Postcontrast fat-suppressed images demonstrate soft-tissue enhancement emanating from the retromolar trigone region (black arrow), with growth into the posterior margin of the left maxilla and abutting the coronoid region of the left mandible. There is likely perineural spread as seen on the axial scan with enhancement into the inferior alveolar canal (white arrow).
| |
View larger version (74K):
[in a new window]
|
Fig 11. Nasopharyngeal carcinoma with infiltration of the prevertebral musculature, skull base, and cavernous sinus. A, Postcontrast fat-suppressed T1-weighted scan shows a large nasopharyngeal carcinoma, which demonstrates contrast enhancement of the prevertebral musculature on the left side (arrow). B, Note the growth through the foramen ovale (arrow) into the Meckel cave and cavernous sinus on the left side via cranial nerve V. C, The cavernous sinus extension on this axial postgadolinium fat-suppressed scan is well demonstrated (arrow). There may also be enhancement in the pterygopalatine fossa on the left side.
| |
View larger version (76K):
[in a new window]
|
Fig 12. A and B, Orbital infiltration. Postcontrast fat-suppressed T1-weighted scans show soft-tissue infiltration in the superior medial aspect of the left orbit, with irregular margins in the extraconal fat. Although there are portions of the tumor in which there still appears to be periosteum containing the tumor, the irregular margins seen more anteriorly (arrow) suggest infiltration requiring orbital surgery.
| |
View larger version (47K):
[in a new window]
|
Fig 13. Orbital infiltration. A, Soft tissue is seen in the posterior left orbit in this patient with metastatic disease to the bone. The infiltration of the intraconal fat suggests the need for orbital exenteration surgery, if surgical treatment is even contemplated. B, Note the erosion at the junction of the posterior left orbit with the frontal bone. C, One can see that there is dural extension of the tumor accompanying the orbital infiltration (arrows).
| |
View larger version (65K):
[in a new window]
|
Fig 14. A, Nodal metastases from breast cancer (short white arrow) are seen to infiltrate the anterior scalene muscle (a) and the hypodense brachial plexus (long white arrow) on this enhanced axial CT image. A tongue of nodal disease indents the plexus beyond the anterior scalene muscle.
B, This same nodal mass (N) infiltrates the anterior mediastinum and abuts on the supraortic vessels in the left.
| |
