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AJNR - American Journal of Neuroradiology

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Copper Deficiency Myeloneuropathy Resembling B₁₂ Deficiency: Partial Resolution of MR Imaging Findings with Copper Supplementation

B.P. Goodman^a, B.W. Chong^b, A.C. Patel^b, G.P. Fletcher^b and B.E. Smith^a

^a Department of Neurology, Mayo Clinic Scottsdale, Scottsdale, Ariz
^b Department of Radiology, Mayo Clinic Scottsdale, Scottsdale, Ariz

View larger version (120K): [in a new window]   Fig 1. A and B, Sagittal (A) and axial (B) fast spin-echo images of the cervical spine before treatment demonstrate diffuse increase in signal intensity (arrows) involving the dorsal columns of the cervical spinal cord extending from C1 to C7.

View larger version (126K): [in a new window]   Fig 2. A and B, T2-weighted sagittal (A) and axial (B) images after copper supplementation show marked resolution of signal intensity (arrows) in the cervical spinal cord.