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AJNR - American Journal of Neuroradiology

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Contrast-Enhanced MR Angiography at 3T in the Evaluation of Intracranial Aneurysms: A Comparison with Time-of-Flight MR Angiography

K. Nael^a, J.P. Villablanca^a, R. Saleh^a, W. Pope^a, A. Nael^a, G. Laub^b and J.P. Finn^a

^a Department of Radiological Sciences, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, Calif
^b Siemens Medical Solutions, Erlangen, Germany

View larger version (87K): [in a new window]   Fig 1. Coronal and sagittal oblique maximum intensity projection (MIP) and 3D volume-rendered projections from contrast-enhanced MRA (upper row) and TOF-MRA (lower row) show a small inferiorly projecting saccular aneurysm (arrows) in the AcomA with maximal diameter measurement of 2.6 x 3.1 mm.

View larger version (40K): [in a new window]   Fig 2. A, Coronal MIP projection from contrast-enhanced MRA shows the supra-aortic arteries with voxel dimensions of 0.7 x 0.6 x 0.8 during 20 seconds. B, Sagittal and axial MIPs from contrast-enhanced MRA (upper row) and TOF-MRA (lower row) show a 20 x 16 mm aneurysm arising from the basilar artery tip. Note the only portion of the aneurysm sac that is visualized on the TOF-MRA study is the superior portion (inflow zone) of the dome (arrows). The loss of signal intensity and incomplete enhancement of the aneurysm sac at TOF-MRA make the full sac size and geometry difficult to perceive.

View larger version (79K): [in a new window]   Fig 3. Coronal oblique MIP and volume-rendered projections from contrast-enhanced MRA (upper row) and TOF-MRA (lower row) show a large (16 x 12 mm) aneurysm arising from the cavernous portion of the right internal carotid artery. Note loss of signal intensity and incomplete flow-related enhancement of the aneurysm sac at TOF-MRA, which limits definition of the border of the aneurysm.

View larger version (11K): [in a new window]   Fig 4. A, Scatterplot shows significant correlation (r = 0.91, 95% CI = 0.87 to 0.96) for aneurysmal dimension measurements between TOF and contrast-enhanced MRA. B, Bland-Altman plot shows differences of no more than 2 mm between aneurysmal dimension measurements on contrast-enhanced MRA and those on TOF-MRA.