AJDRAJNR - American Journal of Neuroradiology

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Inglese, M.
Right arrow Articles by Gonen, O.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Inglese, M.
Right arrow Articles by Gonen, O.

Whole-Brain N-Acetylaspartate Spectroscopy and Diffusion Tensor Imaging in Patients with Newly Diagnosed Gliomas: A Preliminary Study

M. Inglesea, S. Browna, G. Johnsona, M. Lawa, E. Knoppa and O. Gonena

a From the Department of Radiology, New York University School of Medicine, NY


Figure 1
View larger version (59K):

[in a new window]
  		Fig 1. A, Top left, axial T2-weighted MR image of a section containing the lesion (mixed glioneurocytoma grade II) in patient 4 in the Table.

B, Top right, postcontrast T1-weighted image of the same section.

C, Bottom left, DTI (b = 0) image from the same level as A and B and the contralateral NAWM ROIs used for the MD and FA analyses 3.

D, Bottom right, color-coded MD map of the same section showing the marked elevated MD in the tumor and surrounding tissue, analogous to regions 1 and 2 in C. Note that the ROI selected does not contain any apparent tissue abnormalities.


Figure 2
View larger version (10K):

[in a new window]
  		Fig 2. Scatterplot of WBNAA versus MD for the 10 patients (black circles) and 9 controls (white circles). The WBNAA deficit strongly inversely correlates with MD increase (r = –0.879, P = .01) in patients (WBNAA = –18.69.MD + 27.65, solid line) but not in controls (r = 0.012, P = .975, dashed line).





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X