Advanced

AJNR - American Journal of Neuroradiology

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Hill, M.D. Search for Related Content PubMed PubMed Citation Articles by Hill, M.D.

Multicenter Evaluation of a Self-Expanding Carotid Stent System with Distal Protection in the Treatment of Carotid Stenosis

M.D. Hill^a, W. Morrish^a, G. Soulez^b, A. Nevelsteen^c, G. Maleux^d, C. Rogers^e,f, K.E. Hauptmann^g, A. Bonafé^h, R. Beyarⁱ, L. Grubergⁱ, J. Schofer^j for the MAVErIC International Investigators

^a Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
^b Université de Montreal, Department of Radiology, CHUM-Notre Dame, Montréal, Québec, Canada
^c Department of Vascular Surgery, University Hospital Gasthuisberg, Leuven, Belgium
^d Center for Vascular Diseases, Section of Interventional Radiology, University Hospital Gasthuisberg, Leuven, Belgium
^e Cardiovascular Division, Brigham and Women’s Hospital, Boston, Mass
^f Harvard-MIT Division of Health Sciences and Technology, Cambridge, Mass
^g Krankenhaus der Barmherzigen Brüder, Trier, Germany
^h Faculty of Medicine, Montpellier University Hospital Center, Montpellier-Nimes, France
ⁱ Division of Invasive Cardiology, Rambam Medical Center, Technion-Israel Institute of Technology, Haifa, Israel
^j Center for Cardiology and Vascular Intervention, Hamburg, Germany

View larger version (42K): [in a new window]   Fig 1. The Interceptor distal embolic protection device. A, Closed (0.0039-inch crossing profile). B, Open, showing the 1800-µm proximal openings.

View larger version (15K): [in a new window]   Fig 2. Percent diameter stenosis in carotid arteries over time, as determined by sonography evaluation (core laboratory analysis). prox, proximal; dist, distal. The following criteria were used for determination of %DS: PSV (peak systolic velocity) 125 cm/s: <49% DS; PSV > 125 cm/s and EDV (end diastolic velocity) 140 cm/s: 50%–79% DS; PSV > 125 cm/s and EDV > 140 cm/s: 80%–99% DS; no flow in ICA: 100% DS.

View larger version (13K): [in a new window]   Fig 3. Particulate size distribution results compared with GuardWire+ positive controls.

View larger version (92K): [in a new window]   Fig 4. H&E staining of particulate demonstrating diverse cellular elements including macrophages and foam cells (200x).