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Combinations of the Presence or Absence of Cerebral Microbleeds and Advanced White Matter Hyperintensity as Predictors of Subsequent Stroke Types

H. Nakaa, E. Nomurac, T. Takahashia, S. Wakabayashib, Y. Mimoria, H. Kajikawab, T. Kohriyamac and M. Matsumotoc

a Department of Neurology, Suiseikai Kajikawa Hospital
b Department of Neurosurgery, Suiseikai Kajikawa Hospital
c Department of Clinical Neuroscience and Therapeutics, Hiroshima University, Graduate School of Biomedical Sciences


Figure 1
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Fig 1. MR and CT images obtained from a patient (70-year-old man) with intracerebral hemorrhage in the cerebellum, who had been treated with aspirin after the occurrence of lacunar infarction. A and B, Initial T2*-weighted gradient-echo images (TR/TE, 800/26; flip angle, 20°) show multiple microbleeds in the brain stem, cerebellum, basal ganglia, and cerebral hemispheres. C and D, T2-weighted spin-echo images (TR/TE, 4500/112) do not show advanced white matter hyperintensity. E and F, CT image (E) and T2*-weighted gradient-echo image (F) obtained 9 months after the lacunar infarction show occurrence of cerebellar hemorrhage.


Figure 2
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Fig 2. MR images obtained from a patient (85-year-old woman) with lacunar infarction in the right internal capsule after the occurrence of lacunar infarction in the right corona radiata. A and B, Initial T2*-weighted gradient-echo images (TR/TE, 800/26; flip angle, 20°) show no microbleeds. C, T2-weighted spin-echo image (TR/TE, 4500/112) shows advanced white matter hyperintensity. D, Diffusion-weighted image (single-shot echo-planar spin-echo sequence; TR/TE, 5300/135; b = 1000 mm2/s) obtained 23 months after the lacunar infarction shows a hyperintense lesion in the right internal capsule, consistent with acute infarction.