Advanced

AJNR - American Journal of Neuroradiology

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Taoka, T. Articles by Kichikawa, K. Search for Related Content PubMed PubMed Citation Articles by Taoka, T. Articles by Kichikawa, K.

Diffusion Anisotropy and Diffusivity of White Matter Tracts Within the Temporal Stem in Alzheimer Disease: Evaluation of the "Tract of Interest" by Diffusion Tensor Tractography

T. Taoka^a, S. Iwasaki^b, M. Sakamoto^a, H. Nakagawa^a, A. Fukusumi^a, K. Myochin^a, S. Hirohashi^a, T. Hoshida^c and K. Kichikawa^a

^a Department of Radiology, Nara Medical University
^b Department of Radiology, Higashiosaka City General Hospital
^c Department of Neurosurgery, Nara Prefectural Nara Hospital, Nara, Japan

View larger version (106K): [in a new window]   Fig 1. Tractographies were drawn by using diffusion-weighted images (EPI imaging: TR/TE, 2300/122 ms; b = 1000 seconds/mm2; 6-axis encoding; FOV, 230 mm; matrix, 128 x 128; section spacing, 3.3 mm; section thickness, 3 mm; averaging, 6). Tractographies of the inferior occipitofrontal fasciculus (green), uncinate fasciculus (blue), and Meyer’s loop (yellow are shown). A, 3D view from the right upper; B, view from the bottom; C, view from the right; D, view from the front. Mean FA and ADC values were measured along these tracts of interest separately.

View larger version (29K): [in a new window]   Fig 2. Comparison of mean FA, ADC, and number of voxels between patients with AD and controls. The patients with AD had significantly lower mean FA than the controls at both sides of the uncinate fasciculus and at the left side of the inferior occipitofrontal fasciculus (A). The patients with AD had significantly higher mean ADC than the controls at both sides of the uncinate fasciculus and inferior occipitofrontal fasciculus (B). There were no statistically significant differences between AD and controls for the number of voxels of the 3 tracts (C). R indicates right side; L, left side.