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AJNR - American Journal of Neuroradiology

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Magnetic Resonance Imaging for the Detection of Nasopharyngeal Carcinoma

A.D. King^a, A.C. Vlantis^b, R.K.Y. Tsang^b, T.M.K. Gary^c, A.K.Y. Au^a, C.Y. Chan^a, S.Y. Kok^a, W.T. Kwok^a, H.K. Lui^a and A.T. Ahuja^a

^a Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
^b Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
^c Department of Anatomical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China

View larger version (154K): [in a new window]   Fig 1. Axial T1-weighted MR image postcontrast of the nasopharynx of a patient with proved NPC (group 1) undergoing staging with a small cancer confined to the left side of the nasopharynx (arrows) (stage T1).

View larger version (137K): [in a new window]   Fig 2. Axial T1-weighted contrast-enhanced MR image of a patient with suspected NPC (group 2) with a normal nasopharynx (arrows show normal enhancing mucosa).

View larger version (103K): [in a new window]   Fig 3. Axial T1-weighted contrast-enhanced MR image of the nasopharynx in 2 patients with suspected NPC (group 2) where cancer was initially missed by endoscopy and biopsy but identified by MR imaging. Patient with a small cancer in the left fossa of Rosenmuller (arrows) (stage T1) (A) and patient with a small cancer over the torus tubarius (arrows) (stage T1) (B).

View larger version (97K): [in a new window]   Fig 4. Axial T1-weighted contrast-enhanced MR image of the nasopharynx in a patient with suspected NPC (group 2) where MR imaging incorrectly diagnosed cancer that was later shown by biopsy to be lymphoid hyperplasia. A, Section at the level of the fossa of Rosenmuller shows mucosal abnormality in the fossa bilaterally (arrows), giving the false-positive result on MR imaging for cancer. B, Section at the level of the roof shows the "striped" appearance of normal lymphoid tissue in the adenoids (arrows).