Diffusion-Weighted Cranial MR Imaging Findings in a Patient with Hemophagocytic Syndrome
B. Ozgena,
K. Karli-Oguza,
B. Sarikayaa,
B. Tavilb and
A. Gurgeyb
a Departments of Radiology, Hacettepe University, Faculty of Medicine, Ankara, Turkey
b Pediatric Hematology, Hacettepe University, Faculty of Medicine, Ankara, Turkey
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Fig 1. A, Noncontrast axial CT demonstrates low-attenuation lesion in the left frontal subcortical region (arrow).
B, Contrast-enhanced axial CT from the same level shows peripheral nodular enhancement at the left frontal lesion and low attenuation within the vermis (curved arrow).
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Fig 2. A, Axial T2-weighted TSE (4000/99 [TR/TE]) image shows a large vermian mass with a complete hemorrhagic ring and surrounding edema. A small right cerebellar hyperintense lesion is also seen.
B, Postcontrast sagittal T1-weighted SE (550/15) image demonstrates ring enhancement of the vermian lesion.
C and D, DWI (2800/78; b of 0, 500, 1000 seconds/mm2 in 3 axes; 256 x 256 matrix; 230 mm FOV; C) and ADC (D) images show decreased diffusion at the center of the vermian lesion as well as at the right cerebellar lesion.
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Fig 3. A, Axial T2-weighted TSE (4000/99) image shows cortical hyperintense lesions (arrows).
B, Postcontrast axial T1-weighted SE (550/15) image reveals peripheral enhancement of the lesions. C and D, DWI (2800/78; b of 0, 500, 1000 seconds/mm2 in 3 axes; 256 x 256 matrix; 230 mm FOV; C) and ADC (D) images show restricted diffusion of the lesions (note that the lesions are much more conspicuous on this sequence).
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