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AJNR - American Journal of Neuroradiology

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Multiple Reversible MR Signal Changes Caused by Epstein-Barr Virus Encephalitis

G. Hagemann^a, H.-J. Mentzel^b, H. Weisser^c, A. Kunze^a and C. Terborg^a

^a Department of Neurology, Friedrich-Schiller-University, Jena, Germany
^b Institute of Diagnostic and Interventional Radiology, Friedrich-Schiller-University, Jena, Germany
^c Institute of Medical Microbiology, Friedrich-Schiller-University, Jena, Germany

View larger version (134K): [in a new window]   Fig 1. Initial MR imaging of the patient. T1-weighted image does not reveal any abnormality (A). T2-weighted image depicts high signal intensity in the SCC (B). Turbo spin-echo FLAIR sequence shows additional high signals in both posterior hemispheres (C). All lesions had clearly elevated diffusion coefficients with high signal intensity on DWI (D), whereas ADC maps in the splenium were decreased (E). The T1-weighted image with gadolinium shows no contrast enhancement.

View larger version (102K): [in a new window]   Fig 2. MR imaging oft the patient on follow-up 3 weeks later. All signal intensities are normalized (A, FLAIR; B, DWI; ADC maps, not shown).