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Creutzfeldt-Jakob Disease: Comparative Analysis of MR Imaging Sequences

K. Kallenberga,b, W.J. Schulz-Schaefferc, U. Jastrowd, S. Poserd, B. Meissnerd, H.J. Tschampae, I. Zerrd and M. Knautha

a Departments of Neuroradiology, Georg-August University Medical Center, Goettingen, Germany
b MR Research in Neurology and Psychiatry, Georg-August University Medical Center, Goettingen, Germany
c Neuropathology, Georg-August University Medical Center, Goettingen, Germany
d Neurology, Georg-August University Medical Center, Goettingen, Germany
e Department of Radiology, University Hospital, Bonn, Germany


Figure 1
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  		Fig 1. T2-weighted, PD-weighted, FLAIR, and DWI images showing cortical abnormalities in the right parietal lobe; FLAIR and DWI also show abnormalities in the left hemisphere and the dorsal part of the cingulate gyrus.


Figure 2
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  		Fig 2. Relative distribution of signal abnormalities of particular MR sequences in specified anatomical regions.


Figure 3
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  		Fig 3. DWI and ADC showing decreased diffusivity in the basal ganglia and the thalamus as well as in the cortex.


Figure 4
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  		Fig 4. Progression of decreased diffusivity in the basal ganglia (especially the putamen), thalamus, and cortex (time course, 3 months).





Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X