Global and Region-Specific Analyses of Apparent Diffusion Coefficient in Dentatorubral-Pallidoluysian Atrophy
T. Kina,
M. Hiranoa,
T. Taokab,
Y. Furiyaa,
H. Kataokaa,
K. Kichikawab and
S. Uenoa
a Department of Neurology, Nara Medical University, Kashihara, Nara, Japan
b Department of Radiology, Nara Medical University, Kashihara, Nara, Japan
View larger version (14K):
[in a new window]
|
Fig 1. Histogram analyses. Representative measurements of a control subject, a patient with juvenile-onset DRPLA, and a patient with adult-onset DRPLA are plotted (left). The peak heights were lower and peak locations higher in patients with DRPLA than in controls, with greater changes in adult-onset disease. Mean ADC values were significantly higher in patients with DRPLA (P) than in age- and sex-matched control subjects (C) (center). Mean ADC values were higher in adult-onset disease than in juvenile-onset disease (right).
| |
View larger version (34K):
[in a new window]
|
Fig 2. Region of interest (ROI) analyses. ROIs were set in the globus pallidus (white arrowhead), thalamus (black arrowhead), temporal white matter (white arrow), and cerebellum (black arrow). The ADC values in the globus pallidus and cerebellum of patients with DRPLA (P) were significantly higher than those of age- and sex-matched control subjects (C). In contrast, the ADC values did not differ in the thalamus. ADC values in the white matter were higher in patients with adult-onset disease (AP) than in age-matched control subjects (AC). ADC values in the white matter did not differ significantly between patients with juvenile-onset disease (JP) and age- and sex-matched control subjects (JC).
| |
