Advanced

AJNR - American Journal of Neuroradiology

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Hill, M.D. Search for Related Content PubMed PubMed Citation Articles by Hill, M.D.

Using the Baseline CT Scan to Select Acute Stroke Patients for IV-IA Therapy

M.D. Hill^a, A.M. Demchuk^a, T.A. Tomsick^b, Y.Y. Palesch^c, J.P. Broderick^b on behalf of the IMS-1 Investigators

^a From the Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
^b the Cincinnati Stroke Program, Department of Neurology and Stroke, University of Cincinnati, Cincinnati, Ohio
^c the Department of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, SC

View larger version (97K): [in a new window]   Fig 1. A, Baseline CT scan at 100 minutes from stroke onset showing a left middle cerebral artery infarct with an ASPECT score of 8. Points are taken off for hypoattenuation of the head of caudate and the lentiform nuclei. Based upon our data, this patient would be an ideal candidate for IV-IA therapy. B, Baseline CT scan at 175 minutes from stroke onset showing a well-evolved right middle cerebral artery infarct with an ASPECT score of 0. Based upon our data, this patient could be harmed by IV-IA therapy.

View larger version (20K): [in a new window]   Fig 2. Modified Rankin Scale outcomes at 90 days stratified by the baseline ASPECT score and adjusted using ordered logistic regression for baseline age, NIH Stroke Scale score, onset-to-treatment time, and baseline serum glucose.