Advanced

AJNR - American Journal of Neuroradiology

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Turk, A.S. Articles by Mistretta, C. Search for Related Content PubMed PubMed Citation Articles by Turk, A.S. Articles by Mistretta, C.

Physiologic and Anatomic Assessment of a Canine Carotid Artery Stenosis Model Utilizing Phase Contrast with Vastly Undersampled Isotropic Projection Imaging

A.S. Turk^a,c, K.M. Johnson^b, D. Lum^a, D. Niemann^a,c, B. Aagaard-Kienitz^a,c, D. Consigny^a, J. Grinde^a, P. Turski^a, V. Haughton^a and C. Mistretta^b

^a Department of Radiology, University of Wisconsin Hospital and Clinics, Madison, Wis
^b Medical Physics, University of Wisconsin Hospital and Clinics, Madison, Wis
^c Neurosurgery, University of Wisconsin Hospital and Clinics, Madison, Wis

View larger version (99K): [in this window] [in a new window]   Fig 1. Sample carotid stenosis images from contrast-enhanced MRA (A), PC-VIPR MRA (B), 3D Time of Flight MRA (C), and DSA (D).

View larger version (18K): [in this window] [in a new window]   Fig 2. Sample dynamic pressure curve (A) and average pressure color map (B) from the PC-VIPR technique obtained across the carotid artery stenosis.

View larger version (16K): [in this window] [in a new window]   Fig 3. Plot showing correlation of actual measured microcatheter values versus calculated pressure gradients from PC-VIPR across the stenosis.

View larger version (16K): [in this window] [in a new window]   Fig 4. Bland-Altman plot showing the correlation of the logarithm-transformed actual measured microcatheter values versus the logarithm-transformed calculated pressure gradients from PC-VIPR across the stenosis. Dashed line represents the 95% CI at –0.33 and 0.46.

View larger version (63K): [in this window] [in a new window]   Fig 5. Sample arterial waveform tracings from the microcatheter at least 1 cm distal to the carotid stenosis (top row), at the level of the stenosis (middle row), and at least 1 cm proximal to the stenosis (bottom row). The adjacent values represent the mean arterial pressures as well as the systolic (S) and diastolic (D) values generated by the Propaq arterial pressure monitor.

View larger version (16K): [in this window] [in a new window]   Fig 6. Plot showing that pressure changes are identified at all of the observed degrees of stenosis with weak correlation between the degree of stenosis and the pressure gradient due to a high variability in pressure changes.