AJDRAJNR - American Journal of Neuroradiology

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Intracranial Aspergillosis Involving the Internal Auditory Canal and Inner Ear in an Immunocompetent Patient

Y.-S. Choa, D.K. Leea, S.D. Honga and W.S. Ohb

a Department of Otorhinolaryngology-Head and Neck Surgery Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135–710, Korea
b Division of Infectious Diseases Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135–710, Korea


Figure 1
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Fig 1. MR images of a patient diagnosed as having aspergillosis involving the left inner ear and IAC. These images were obtained in November 2004.

A, Axial T2-weighted MR image shows an area of low signal intensity replacing normal high signal intensity in the cochlea (white arrow). A soft-tissue masslike lesion filling the left IAC is also seen (arrowhead).

B, Enhanced T1-weighted axial image shows the intense enhancement of the left inner ear and IAC (arrows).


Figure 2
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Fig 2. Follow-up MR image obtained in January 2005. Enhanced T1-weighted image shows abnormal enhancement of the IAC with a nonenhancing region centrally (arrow). Markedly thickened dural enhancement is also noted adjacent to the left IAC (arrowhead). The progression of an enhancing lesion toward the brain stem is noted (empty arrow).


Figure 3
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Fig 3. Photomicrograph obtained from histologic examination of the necrotic neural tissue debris from the IAC shows the characteristic branching septate hyphae of Aspergillosis organisms (white arrow) (Grocott’s methenamine silver, original magnification x200).