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Focal Brain Glucose Hypometabolism in Patients with Neuropsychologic Deficits after Diffuse Axonal Injury

T. Nakashimaa, N. Nakayamaa, K. Miwaa, A. Okumuraa, A. Soedab and T. Iwamab

a Department of Neurosurgery, Chubu Ryogo Center, Kizawa Memorial Hospital
b Department of Neurosurgery, Graduate School of Medicine, Gifu University


Figure 1
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Fig 1. Z-score brain surface map represents areas of metabolic reduction in patients in comparison with healthy subjects (data base group). Right lateral (R.LAT), left lateral (L. LAT), superior (SUP), inferior (INF), anterior (ANT), posterior (POST), right medial (R. MED), and left medial (L. MED) views are shown. Reduction of glucose metabolism is evident in medial aspects of cerebrum especially in cingulate gyrus, lingual gyrus, and cuneus.


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Fig 2. Z-score brain surface map represents the result of group comparison between 2 healthy subjects groups such as control group (CG) and data base group (DBG). Right lateral (R.LAT), left lateral (L. LAT), superior (SUP), inferior (INF), anterior (ANT), posterior (POST), right medial (R. MED), and left medial (L. MED) views are shown. Marked metabolic reduction is not shown on the medial surface of cerebrum.


Figure 3
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Fig 3. Z-score brain surface map of representative cases shows a prominent metabolic reduction on respective gyrus level segment in cingulate gyrus.

Top, 46-year-old man (case 4) shows hypometabolism in anterior cingulate gyrus.

Middle, 38-year-old woman (case 7) shows hypometabolism in middle cingulate gyrus. Metabolic reduction shown in the right frontal lobe is the result of cerebral contusion.

Bottom, 28-year-old man (case 12) shows hypometabolism in posterior cingulate gyrus with concomitant hypometabolism of lingual gyrus and cuneus.