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Presence of Activated Microglia in a High-Signal Lesion on T1-Weighted MR Images: A Biopsy Sample Re-Examined

Din-E Shana and Hung-Chi Pana

a Neurologic Institute

Donald M.T. Hob

b Department of Pathology

Michael M.H. Tengc

c Department of Radiology
Taipei Veterans General Hospital and National Yang-Ming University
School of Medicine

Chen Changd

d Institute of Biomedical Sciences
Academia Sinica
Taipei, Taiwan, Republic of China


Figure 1
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Fig 1. A, Axial section of T1-weighted (TR/TE/TI, 550/10/1 ms) MR image at the level of the basal ganglia shows hyperintensities in the right putamen and the external segment of globus pallidus (arrow), along with an infarct in the right temporoparietal cortex. B, Immunohistochemical staining of the brain biopsy specimen for CD68 revealed numerous darkly stained microglia with or without dendritic processes (white arrows) (original magnification x100).