Presence of Activated Microglia in a High-Signal Lesion on T1-Weighted MR Images: A Biopsy Sample Re-Examined
Din-E Shana and
Hung-Chi Pana
a Neurologic Institute
Donald M.T. Hob
b Department of Pathology
Michael M.H. Tengc
c Department of Radiology
Taipei Veterans General Hospital and National Yang-Ming University
School of Medicine
Chen Changd
d Institute of Biomedical Sciences
Academia Sinica
Taipei, Taiwan, Republic of China

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Fig 1. A, Axial section of T1-weighted (TR/TE/TI, 550/10/1 ms) MR image at the level of the basal ganglia shows hyperintensities in the right putamen and the external segment of globus pallidus (arrow), along with an infarct in the right temporoparietal cortex. B, Immunohistochemical staining of the brain biopsy specimen for CD68 revealed numerous darkly stained microglia with or without dendritic processes (white arrows) (original magnification x100).
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