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Real-Time Cerebral Angiography: Sensitivity of a New Contrast-Specific Ultrasound Technique

T. Hölschera, J.A. Sattinb, R. Ramanc,d, W. Wilkeninge, C.V. Fanaleb, S.E. Olsonb, R.F. Mattreya and P.D. Lydenb

a Department of Radiology, University of California San Diego, Calif
b Department of Neurology, University of California San Diego, Calif
c Department of Family & Preventive Medicine, University of California San Diego, Calif
d Department of Neurosciences, University of California San Diego, Calif
e Ruhr Center of Excellence for Medical Engineering, Bochum, Germany


Figure 1
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Fig 1. Blooming artifact. Contrast-enhanced transcranial sonography of the circle of Willis (axial scanning plane via the temporal bone window). The vessel delineation is diminished because of the strong contrast signal intensity (blooming) after IV bolus injection of the UCA. Red color-coding represents flow toward the transducer, blue color-coding flow away from it. MCA, middle cerebral artery; MCA contra, middle cerebral artery contralateral; PCA, posterior cerebral artery, PCA contra; posterior cerebral artery contralateral; ACA, anterior cerebral artery.


Figure 2
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Fig 2. Transcranial ultrasound angiography (tUSA). tUSA image of the circle of Willis and its branches after UCA injection. M1, M2, and M3, middle cerebral artery segments; A1 and A2, anterior cerebral artery segments; P1, P2, and P3, posterior cerebral artery segments; BS, brain stem; top of BA, hyperechogenic distal part of the basilar artery.