Defining Optic Nerve Tortuosity
G.T. Armstronga,c,
A.R. Localioc,
T. Feyginb,
L. Bilaniukb,
P.C. Phillipsa,
M.J. Fishera,
B.L. Stromc and
R. Zimmermanb
a Division of Oncology, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine Philadelphia, Pa
b Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine Philadelphia, Pa
c Department of Biostatistics and Epidemiology, Center for Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pa

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Fig 1. Optic glioma.
A, Sagittal spin-echo image (TR, 643 ms; TE, 12 ms) shows markedly enlarged optic nerve (arrow).
B, Axial fast spin-echo (TR, 6000 ms; TE, 84 ms) image shows bilateral enlargement, along with tortuosity of intraorbital optic nerves (arrow).
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Fig 2. Tortuosity of optic nerves
A, Axial fast spin-echo T2-weighted image showing factor 1: interruption of the optic nerve out of the axial plane (tip of arrow) without return.
B, Axial fast spin-echo T2-weighted image showing factor 2: interruption of the optic nerve out of the axial plane (tip of arrow) with return of the nerve into the axial plane.
C, Axial fast spin-echo T2-weighted image showing factor 3: deviation of the optic nerve within the axial plane (arrow).
D, Sagittal T1-weighted image showing factor 4: increased curvature (tip of arrow) in the sagittal plane.
E, Coronal fast spin-echo T2-weighted image showing factor 5: lack of congruity of the optic nerves (arrow) in the coronal plane.
F, Coronal fast spin-echo T2-weighted image showing factor 6: dilation of the subarachnoid space (encircled by arrows) surrounding anterior portion of optic nerves.
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