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AJNR - American Journal of Neuroradiology

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Safety and Feasibility of Intra-Arterial Nicardipine for the Treatment of Subarachnoid Hemorrhage-Associated Vasospasm: Initial Clinical Experience with High-Dose Infusions

J.G. Tejada^a, R.A. Taylor^a, M.S. Ugurel^a, M. Hayakawa^a, S.K. Lee^a and J.C. Chaloupka^a

^a From the Department of Radiology, University of Iowa College of Medicine, Iowa City, Iowa

View larger version (87K): [in this window] [in a new window]   Fig 1. Left vertebral injection left anterior oblique (LAO) (A) and lateral (B) views demonstrate severe vasospasm of the distal basilar artery after SAH secondary to dissecting right vertebral aneurysm, treated with parent vessel occlusion with coils.

View larger version (87K): [in this window] [in a new window]   Fig 2. After a total 40 mg of intra-arterial nicardipine infusion (3 vascular territories injected). Almost total restoration of the vessel diameter is demonstrated.

View larger version (76K): [in this window] [in a new window]   Fig 3. Right internal carotid artery (ICA) injection, lateral projection demonstrates severe vasospasm of the supraclinoid ICA after SAH.

View larger version (76K): [in this window] [in a new window]   Fig 4. After nicardipine infusion, there is more than 60% vessel diameter restoration.