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AJNR - American Journal of Neuroradiology

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Reproducibility of Quantitative CT Brain Perfusion Measurements in Patients with Symptomatic Unilateral Carotid Artery Stenosis

A. Waaijer^a, I.C. van der Schaaf^a, B.K. Velthuis^a, M. Quist^b, M.J.P. van Osch^a,c, E.P.A. Vonken^a, M.S. van Leeuwen^a and M. Prokop^a

^a Department of Radiology, University Medical Center, Utrecht, The Netherlands
^b Philips Medical Systems, Best, The Netherlands
^c Department of Radiology, Leiden University Medical Center, Utrecht, The Netherlands

View larger version (99K): [in this window] [in a new window]   Fig 1. Analysis of manual outlined ROIs according to territorial division of Damasio.26 1, ACA territory; 2, MCA territory; 3, basal ganglia; 4, PCA territory.

View larger version (22K): [in this window] [in a new window]   Fig 2. Bland-Altman plots of the relative differences (interobserver variability, pooled data) against the mean absolute value for CBF (milliliters per 100 g per minute) (A), CBV (milliliters per 100 g) (B), and MTT (seconds) (C). The relative CBV, CBF, and MTT indicate the difference between 2 observations divided by the mean of those 2 observations, given as a percentage. The thick line represents the mean bias, and the dotted lines indicate the upper and lower limits of agreement. These upper and lower limits of agreement for the relative differences were 37% and –37% for CBV, 38% and –43% for CBF, and 21% and –16% for MTT, respectively.