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Analysis of Central Nervous System Vasculitis with Diffusion-Weighted Imaging and Apparent Diffusion Coefficient Mapping of the Normal-Appearing Brain

M.L. Whitea, W.L. Hadleyb, Y. Zhanga and M.A. Dogarc

a Department of Radiology, University of Nebraska Medical Center, Omaha, Neb
b Department of Radiology, University Hospital of Cleveland/Case Medical Center, Cleveland, Ohio
c Department of Radiology, University of Iowa College of Medicine, Iowa City, Iowa


Figure 1
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  		Fig 1. A, Regions of interest 1, 2, and 3 represent measurements made in the anterior, central, and posterior WM in the corona radiata and centrum semiovale. B, The region of interest positions are represented by 4 for the caudate heads, 5 for the putamina, 6 for the posterior internal capsules, and 7 for the thalami. C, Region of interest 8 is positioned in the cerebellar WM.


Figure 2
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  		Fig 2. Comparison of the ADC values (square millimeters per second) between the patients with vasculitis and the healthy controls for anterior WM (WM, A), central WM (B), posterior WM (C), caudate heads (D), putamina (E), thalami (F), posterior internal capsules (post IC, G), and cerebellar WM (H). There is a significant increase in the ADC values (P < .00625) for the anterior WM, central WM, thalami, and post IC in the patients with vasculitis. The horizontal lines indicate the mean ADC values in each group.





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X