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Cerebral Venous Thrombus Signal Intensity and Susceptibility Effects on Gradient Recalled-Echo MR Imaging

J.L. Leachb, W.M. Struba and M.F. Gaskill-Shipleyb

a Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, Ohio
b The Neuroscience Institute, Cincinnati, Ohio


Figure 1
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Fig 1. Signal intensity of thrombosed venous segments without susceptibility effect on GRE T2*- weighted sequences. Black, hypointense relative to gray matter; gray, isointense to gray matter; white, hyperintense to gray matter.


Figure 2
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Fig 2. Signal intensity of thrombosed venous segments with susceptibility effect on GRE T2*- weighted sequences. Black, hypointense relative to gray matter; gray, isointense to gray matter; white, hyperintense to gray matter. GRE*, all segments exhibiting susceptibility effect were hypointense on GRE T2*- weighted sequences.


Figure 3
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Fig 3. A 22-year-old woman with a 6-day history of headache. Note the subtle abnormal signal intensity in the right transverse sinus on T2-weighting (A). The medial sinus is isointense (black arrow, A) and the lateral transverse sinus is hypointense (white arrow, A). The signal intensity on GRE sequences is very dark and enlarged compared with the size of the sinus on other sequences, consistent with susceptibility effect (arrows, B). On the postcontrast T1-weighted image, an isointense filling defect is noted consistent with thrombus (arrows, C).

A, FSE T2-weighted image.

B, GRE T2*-weighted image.

C, T1WI after the administration of contrast.


Figure 4
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Fig 4. Clinical thrombus age and susceptibility effect. Gray, susceptibility effect present; white, susceptibility effect absent.


Figure 5
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Fig 5. A 20-year-old woman with 2-day history of severe headache. Thrombosis of the superior sagittal sinus and multiple cortical veins is present. Note the prominent hypointensity of the thrombosed superior sagittal sinus and cortical veins in B (arrows), much larger than the thrombosed venous structures on other sequences (A and C, arrows). Graded as 3+ susceptibility effect. Signal intensity of the thrombosed segments is hypointense on T2WI and isointense on T1WI. Note the normal parietal cortical vein on the left (arrowheads).

A, FSE T2-weighted image.

B, GRE T2*-weighted image.

C, T1WI after the administration of contrast.