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Bone Formation in Elastase-Induced Rabbit Aneurysms Embolized with Platinum Coils: Report of 2 Cases

D. Daia, Y.H. Dinga, R. Kadirvela, D.A. Lewisa, H.J. Clofta and D.F. Kallmesa

a From the Neuroradiology Research Laboratory, Department of Radiology, Mayo Clinic, Rochester, Minn


Figure 1
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  		Fig 1. A, Lower-power view of H&E staining section of 3-month platinum coil embolized aneurysm, showing the mature bone formation near the neck area (arrow), (H&E, original magnification = x30).

B, Higher-power view of formed bone in A, showing the bony trabeculae (short arrow) and bone marrow (long arrow), which contains loose reticular tissue with blood elements, thin-walled vessels, stromal cells, and adipose cells (H&E, original magnification = x100).


Figure 2
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  		Fig 2. A, Lower-power view of H&E staining section of 1-year platinum coil embolized aneurysm, showing the localized formed bone and marrow within the aneurysm dome (arrow); (H&E, original magnification = x15).

B, Higher-power view of formed bone in A, showing the bony trabeculae (short arrow) and bone marrow (long arrow), which contains various types of blood elements and blood sinusoids (H&E, original magnification = x100).





Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X