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Decrease in the Volume of White Matter Lesions with Improvement of Hepatic Encephalopathy

B. Míngueza,b, A. Rovirac, J. Alonsob,c and J. Córdobaa,b

a From the Servicio de Medicina Interna-Hepatología, Hospital Universitario Valle Hebron, Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona Spain
b Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Hospital Universitario Valle Hebron, Barcelona, Spain
c Unidad de Resonancia Magnética, Servicio de Radiología, Hospital Universitario Valle Hebron, Barcelona, Spain


Figure 1
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  		Fig 1. A, MR image (transverse T2-weighted fast-FLAIR images, 9900 ms/110 ms/2500 ms/1 [TR/TE/inversion time/acquisitions]) obtained in patient 1 at baseline, while showing signs of overt hepatic encephalopathy. The image shows multiple focal supratentorial WMLs (total lesion volume, 7,507 mm3). B, Patient 1 after improvement of hepatic encephalopathy: MR shows a clear reduction in size and number of these focal WMLs (final lesion volume of 2,033 mm3).


Figure 2
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  		Fig 2. A, MR image (transverse T2-weighted fast-FLAIR images, 9900 ms/110 ms/2500 ms/1 [TR/TE/inversion time/acquisitions ]) obtained in patient 1 at baseline, while showing signs of overt hepatic encephalopathy. The scan shows multiple diffuse supratentorial WMLs (total lesion volume, 25,901 mm3). B, Patient 2 after improvement of hepatic encephalopathy: MR shows a clear reduction in size and number of diffuse WMLs (final lesion volume, 16,586 mm3).


Figure 3
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  		Fig 3. A, MR image (transverse T2-weighted fast-FLAIR images, 9900 ms/110 ms/2500 ms/1 [TR/TE/inversion time/acquisitions]) obtained in patient 3 at baseline, while showing signs of overt hepatic encephalopathy. MR shows multiple focal WMLs (total lesion volume, 18,601 mm3). B, Patient 3 after improvement of hepatic encephalopathy: MR shows clear reduction in size and number of focal WMLs (final lesion volume, 10,393 mm3).





Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X