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AJNR - American Journal of Neuroradiology

Published ahead of print on September 20, 2007
doi: 10.3174/ajnr.A0643

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Reliability of MR Perfusion-Weighted and Diffusion-Weighted Imaging Mismatch Measurement Methods

M. Luby^a and S. Warach^a

^a From the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md

View larger version (48K): [in this window] [in a new window]   Fig 1. Mismatch Method 2. DWI sequence (A) is contrasted to maximize the lesion conspicuity (B) and its intensity values are inverted (C) and then blended with the registered MTT sequence (D). Mismatch Method 1 (E): separate lesion measurements on DWI and MTT sequences compared with Mismatch Method 2 (F): single measurement of the blended difference. Mismatch Method 1 (G): separate lesion measurements on DWI and MTT sequences compared with Mismatch Method 2 (H): single measurement of the blended difference with an arrow indicating the larger MTT lesion seen on the blended map.

View larger version (19K): [in this window] [in a new window]   Fig 2. A, Mismatch Method 1, acute time point plot of mean volume vs volume difference between 2 sets of measurements (raw numbers) where the thick black lines represent the upper and lower boundaries using ±2 SDs from the mean. B, Mismatch Method 2, acute time point plot of mean volume vs volume difference between 2 sets of measurements (raw numbers) where the thick black lines represent the upper and lower boundaries using ±2 SDs from the mean. C, Mismatch Method 1, acute time point plot of mean percentage vs percentage difference between 2 sets of measurements (mismatch/MTT percentage) where the thick black lines represent the upper and lower boundaries using ±2 SDs from the mean. D, Mismatch Method 2, acute time point plot of mean percentage vs percentage difference between 2 sets of measurements (mismatch/MTT percentage) where the thick black lines represent the upper and lower boundaries using ±2 SDs from the mean.