AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on September 24, 2007
doi: 10.3174/ajnr.A0673
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Arterial Spin-Labeling and MR Spectroscopy in the Differentiation of Gliomas

S. Chawlaa, S. Wanga, R.L. Wolfa, J.H. Wooa, J. Wanga, D.M. O'Rourkeb, K.D. Judyb, M.S. Gradyb, E.R. Melhema and H. Poptania

a Department of Radiology, University of Pennsylvania, Philadelphia, Penn
b Department of Neurosurgery, University of Pennsylvania, Philadelphia, Penn


Figure 1
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  		Fig 1. Axial T1-weighted MPRAGE image (A) demonstrates a low-grade oligodendroglioma in the left parietal region; CBF map (B) shows voxels from "hyperperfused" (a), "isoperfused" (b), and "hypoperfused" (c) regions. 1H-MRSI spectra (a-c) are from the corresponding voxels shown on the CBF map.


Figure 2
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  		Fig 2. Axial T1-weighted MPRAGE image (A) exhibits a case of GBM in the frontal lobe; CBF map (B) shows voxels from "hyperperfused" (a), "isoperfused" (b), and "hypoperfused" (c) regions of the glioma. 1H-MRSI spectra (a–c) are from the corresponding voxels shown on the CBF map.


Figure 3
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  		Fig 3. Scatterplots demonstrate the variations in ChoG/WM (A), Glx G/WM, (B), and Lip+LacG/CrWM (C) from the "hyperperfused" regions between the low-grade and high-grade gliomas.


Figure 4
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  		Fig 4. Scatterplots demonstrate the variations in ChoG/WM (A), and Lip+LacG/CrWM (B) from the "hyperperfused" regions between the low-grade and high-grade oligodendrogliomas.





Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X