AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on October 18, 2007
doi: 10.3174/ajnr.A0783
This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Linn, J.
Right arrow Articles by Wiesmann, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Linn, J.
Right arrow Articles by Wiesmann, M.

Subarachnoid Hemosiderosis and Superficial Cortical Hemosiderosis in Cerebral Amyloid Angiopathy

J. Linna, J. Hermsb, M. Dichgansc, H. Brückmanna, G. Fesla, T. Freilingerc and M. Wiesmanna

Department of Neuroradiology, University of Munich, Munich, Germany
Zentrum fur Neuropathologie und Prionforschung (ZNP), University of Munich, Munich, Germany
Department of Neurology, University of Munich, Munich, Germany


Figure 1
View larger version (121K):
[in this window]
[in a new window]

  		Fig 1. Patient 1, a 70-year-old woman with global aphasia and severe apraxia. T2*-weighted image demonstrates superficial cortical hemosiderosis in the left parietal cortex (arrows).


Figure 2
View larger version (80K):
[in this window]
[in a new window]

  		Fig 2. Patient 2, a 69-year-old man with severe headache, visual disturbances, and nausea. A,B, T2*-weighted images depict left frontal subarachnoid hemosiderosis (dotted arrows) and left parietal superficial cortical hemosiderosis (arrows).


Figure 3
View larger version (88K):
[in this window]
[in a new window]

  		Fig 3. Patient 3, a 72-year-old woman with histopathologically proved CAA and a large hyperacute right frontal intracerebral macrohemorrhage (thick arrows). A,B, T2*-weighted images demonstrate the hyperacute lobar hemorrhage (thick arrows), subarachnoid hemosiderosis (dotted lines), and superficial cortical hemosiderosis (thin arrows).


Figure 4
View larger version (60K):
[in this window]
[in a new window]

  		Fig 4. A–F, Schematic drawings illustrating subarachnoid hemosiderosis and superficial cortical hemosiderosis. A–D, Coronal schematic drawings, illustrating the time-dependent development of subarachnoid hemosiderosis and superficial cortical hemosiderosis (black, subarachnoid space; white line, pia mater; orange line, arachnoid layer; light blue, dura mater). E,F, Horizontal schematic drawings corresponding to the areas marked with black bars in B and C, demonstrating the visual appearance of subarachnoid hemosiderosis and superficial cortical hemosiderosis on axial sections. A, Normal appearance of the subarachnoid space. B,E, Subarachnoid hemorrhage (red) presenting as a linear signal intensity in the subarachnoid space (E). C, Residues of blood penetrating the pia mater and deposit in the superficial layers of the cerebral cortex. D,F, Superficial cortical hemosiderosis, defined as linear residues of blood in the superficial layers of the cerebral cortex (dark red). Superficial cortical hemosiderosis typically has a bilinear "tracklike" appearance on axial sections, caused by the signal intensity of the normal-appearing subarachnoid space in the middle, which is bordered bilaterally by linear deposits of hemosiderin in the superficial layers of the adjacent cortex (F).





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X