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AJNR - American Journal of Neuroradiology

Published ahead of print on September 3, 2008
doi: 10.3174/ajnr.A1238

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CT Perfusion Quantification of Small-Vessel Ischemic Severity

T.J. Huynh^a, B. Murphy^c,d,e, J.A. Pettersen^f, H. Tu^b, D.J. Sahlas^f, L. Zhang^g, S.P. Symons^h, S. Black^f, T.-Y. Lee^c,d,e and R.I. Aviv^h

^a Department of Medicine, University of Toronto, Toronto, Ontario, Canada
^b Department of Medicine, Queen's University, London, Ontario, Canada
^c Department of Medicine, University of Western Ontario, London, Ontario, Canada
^d Robarts Research Institute, London, Ontario, Canada
^c Lawson Health, Research Institute, London, Ontario, Canada
^e Division of Neurology, Sunnybrook Health Science Centre, Toronto, Ontario, Canada
^f Odette Cancer Centre, Sunnybrook Health Science Centre, Toronto, Ontario, Canada
^g Department of Neuroradiology, Sunnybrook Health Science Centre, Toronto, Ontario, Canada

View larger version (34K): [in this window] [in a new window]   Fig 1. Region-of-interest technique for perfusion determination. Two ROIs are drawn on the average map (A) adjacent to each ventricle for a total of 8 PV ROI's. Two further ROIs are placed within the adjacent subcortical white matter defined by an imaginary line between the ventricle and overlying cortex for a total of 8 SC ROIs. The ROIs are subsequently projected onto the inherently coregistered maps for PV and SC CBF (B), CBV (C) and MTT (D) calculation.